<?xml version="1.0" encoding="UTF-8"?>
<neuroml xmlns="http://morphml.org/neuroml/schema"
xmlns:meta="http://morphml.org/metadata/schema"
xmlns:mml="http://morphml.org/morphml/schema"
xmlns:bio="http://morphml.org/biophysics/schema"
xmlns:cml="http://morphml.org/channelml/schema"
xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
xsi:schemaLocation="http://morphml.org/neuroml/schema http://www.neuroml.org/NeuroMLValidator/NeuroMLFiles/Schemata/v1.8.1/Level2/NeuroML_Level2_v1.8.1.xsd"
length_units="micrometer">
<cells>
<cell name="GranuleCell">
<meta:notes>A single compartment cerebellar Granule Cell model taken from Maex and De Schutter 1998</meta:notes>
<meta:authorList>
<meta:modelAuthor>
<meta:name>Maex, R.</meta:name>
</meta:modelAuthor>
<meta:modelAuthor>
<meta:name>De Schutter, E.</meta:name>
</meta:modelAuthor>
<meta:modelTranslator>
<meta:name>Padraig Gleeson</meta:name>
<meta:institution>UCL</meta:institution>
<meta:email>p.gleeson - at - ucl.ac.uk</meta:email>
</meta:modelTranslator>
</meta:authorList>
<meta:publication>
<meta:fullTitle>Maex, R and De Schutter, E.
Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the
cerebellar Granule Cell Layer. J Neurophysiol, Nov 1998; 80: 2521 - 2537</meta:fullTitle>
<meta:pubmedRef>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9819260&dopt=Abstract</meta:pubmedRef>
</meta:publication>
<meta:neuronDBref>
<meta:modelName>Cerebellar granule cell</meta:modelName>
<meta:uri>http://senselab.med.yale.edu/senselab/neurondb/ndbEavSum.asp?id=7346&mo=2</meta:uri>
</meta:neuronDBref>
<mml:segments>
<mml:segment id="0" name="Soma" cable="0">
<mml:proximal x="0.0" y="0.0" z="0.0" diameter="10.0"/>
<mml:distal x="0.0" y="0.0" z="0.0" diameter="10.0"/>
</mml:segment>
</mml:segments>
<mml:cables>
<mml:cable id="0" name="Soma">
<meta:group>all</meta:group>
<meta:group>soma_group</meta:group>
</mml:cable>
</mml:cables>
<!--Adding the biophysical parameters-->
<biophysics units="Physiological Units">
<bio:mechanism name="Generic_Na" type="Channel Mechanism">
<bio:parameter name="gmax" value="54.6301">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="Generic_H" type="Channel Mechanism">
<bio:parameter name="gmax" value="0.03090506">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="Generic_KA" type="Channel Mechanism">
<bio:parameter name="gmax" value="1.14567">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="Generic_KDr" type="Channel Mechanism">
<bio:parameter name="gmax" value="8.89691">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="PassiveCond_Gran" type="Channel Mechanism">
<bio:parameter name="gmax" value="0.0330033">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="Generic_CaHVA" type="Channel Mechanism">
<bio:parameter name="gmax" value="0.9084216">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name="Generic_KCa" type="Channel Mechanism">
<bio:parameter name="gmax" value="17.9811">
<bio:group>all</bio:group>
</bio:parameter>
</bio:mechanism>
<bio:mechanism name = "CaPool" type = "Ion Concentration">
<!-- Note: not adding gmax for Ion Concentration. Value for scaling factor
to apply to current to get change in conc should be determined from ChannelML
file for the CaPool... -->
</bio:mechanism>
<bio:spec_capacitance>
<bio:parameter value="1.0">
<bio:group>all</bio:group>
</bio:parameter>
</bio:spec_capacitance>
<bio:spec_axial_resistance>
<bio:parameter value="0.1">
<bio:group>all</bio:group>
</bio:parameter>
</bio:spec_axial_resistance>
<bio:init_memb_potential>
<bio:parameter value="-65.0">
<bio:group>all</bio:group>
</bio:parameter>
</bio:init_memb_potential>
<bio:ion_props name = "h">
<bio:parameter name = "e" value = "-42.0">
<bio:group>all</bio:group>
</bio:parameter>
</bio:ion_props>
<bio:ion_props name = "k">
<bio:parameter name = "e" value = "-90.0">
<bio:group>all</bio:group>
</bio:parameter>
</bio:ion_props>
<bio:ion_props name = "na">
<bio:parameter name = "e" value = "55.0">
<bio:group>all</bio:group>
</bio:parameter>
</bio:ion_props>
<bio:ion_props name = "ca">
<bio:parameter name = "conc_e" value = "2.4E-6">
<bio:group>all</bio:group>
</bio:parameter>
<bio:parameter name = "conc_i" value = "7.55E-11">
<bio:group>all</bio:group>
</bio:parameter>
</bio:ion_props>
</biophysics>
</cell>
</cells>
</neuroml>
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