<?xml version="1.0" encoding="UTF-8"?>

<channelml xmlns="http://morphml.org/channelml/schema"
    xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
    xmlns:meta="http://morphml.org/metadata/schema"
    xsi:schemaLocation="http://morphml.org/channelml/schema http://www.neuroml.org/NeuroMLValidator/NeuroMLFiles/Schemata/v1.8.0/Level2/ChannelML_v1.8.0.xsd"
    units="Physiological Units">

    <meta:notes>ChannelML file containing a single Channel description</meta:notes>

    <channel_type name="KConductance">
        
        <status value="stable">
            <meta:comment>Equations adapted from HH paper for modern convention of external potential being zero</meta:comment>
            <meta:contributor>
                <meta:name>Padraig Gleeson</meta:name>
            </meta:contributor>
        </status>
        
        <meta:notes>Simple example of K conductance in squid giant axon. Based on channel from Hodgkin and Huxley 1952</meta:notes>
        
        <meta:authorList>
            <meta:modelTranslator>
                <meta:name>Padraig Gleeson</meta:name>
                <meta:institution>UCL</meta:institution>    
                <meta:email>p.gleeson - at - ucl.ac.uk</meta:email>
            </meta:modelTranslator>
        </meta:authorList>

        <meta:publication>
            <meta:fullTitle>A. L. Hodgkin and A. F. Huxley, A quantitative description of membrane current and its application
            to conduction and excitation in nerve, J. Physiol., vol. 117, pp. 500-544, 1952.</meta:fullTitle>
            <meta:pubmedRef>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=12991237</meta:pubmedRef>
        </meta:publication>

        <meta:neuronDBref>
            <meta:modelName>K channels</meta:modelName>
            <meta:uri>http://senselab.med.yale.edu/senselab/NeuronDB/channelGene2.htm#table3</meta:uri>
        </meta:neuronDBref>
        
        <current_voltage_relation cond_law="ohmic" ion="k" default_gmax="36" default_erev="-77.0">
            
            <gate name="n" instances="4">
                <closed_state id="n0"/>
                <open_state id="n"/>
                    
                <transition name="alpha" from="n0" to="n" expr_form="exp_linear"
                            rate="0.1" scale="10" midpoint="-55" />
                <transition name="beta" from="n" to="n0" expr_form="exponential"
                            rate="0.125" scale="-80" midpoint="-65" />
                    
            </gate>
        </current_voltage_relation>
        
    </channel_type>
</channelml>